NEW YORK (AP) — Stocks that moved substantially or traded heavily Wednesday on the New York Stock Exchange and the Nasdaq stock market:
Chipotle Mexican Grill Inc., down $22.36 to $426.67
The fast-food chain received a federal grand jury subpoena as the government looks into a norovirus outbreak at a California restaurant.
TherapeuticsMD Inc., down 93 cents to $8.38
The women's health products company is publicly offering $125 million in stock and will used proceeds for sales and development.
Valeant Pharmaceuticals International Inc., up $1.54 to $102.40
The drug developer named Howard Schiller as interim CEO to replace Michael Pearson, who remains hospitalized from pneumonia.
AutoNation Inc., down $5.98 to $50.76
The auto retailer had to offer large discounts in December and will report smaller profits per vehicle in the fourth quarter.
Netflix Inc., up $10.02 to $117.68
The video streaming company said it was launching its service globally and added service in several new languages including Arabic and Korean.
Conatus Pharmaceuticals Inc., up 1 cent to $2.88
The biotechnology company reported positive results from a mid-stage study on a potential treatment for liver diseases.
Epizyme Inc., down $3.58 to $11.54
The biotechnology company plans to publicly offer $120 million in stock, mainly to fund development of cancer treatments.
Cempra Inc., down $3.99 to $24.74
The drug developer plans to offer $175 million in stock to fund development of antibiotics for bacterial infectious diseases.