European Committee for Medicinal Products for Human Use (CHMP) adopts Positive Opinion for TWYNSTA®, Boehringer Ingelheim’s new single pill combination hypertension treatment

TWYNSTA®, the combination of telmisartan (the only angiotensin receptor blocker (ARB) with a broad cardiovascular protection indication) and amlodipine, provides effective and consistent blood pressure (BP) reduction throughout 24 hours

Ingelheim, 26 July, 2010 – Boehringer Ingelheim announced today that the European Committee for Medicinal Products for Human Use (CHMP) adopted a Positive Opinion for the approval of TWYNSTA®. It will be indicated in adults whose blood pressure is not adequately controlled on amlodipine and is also indicated as replacement therapy in adult patients receiving telmisartan and amlodipine from separate tablets can instead receive tablets of TWYNSTA containing the same component doses.

Once approved, the new single pill combination (TWYNSTA®) will provide patients and prescribers with a highly effective combination of telmisartan, an angiotensin receptor blocker (ARB), and amlodipine, a calcium-channel blocker (CCB), for the treatment of hypertension. It will reduce blood pressure effectively and safely in a broad range of patient groups including those with mild, moderate and severe hypertension as well as hypertensive patients at high cardiovascular risk, such as those with diabetes or metabolic syndrome. 1-8