NEW YORK (AP) — Stocks that moved substantially or traded heavily Tuesday:
McKesson Corp., up $3.95 to $176.58
The prescription drug distributer announced an acquisition and said it will spin off one business and pursue strategic options for another.
ReachLocal Inc., up $2.87 to $4.56
USA Today publisher Gannett said it will buy the digital marketing company for $4.60 per share, or $138.4 million.
Xencor Inc., up $4.02 to $16.56
The drug developer announced a partnership with Novartis to develop potential cancer drugs and will get $150 million up front.
Regulus Therapeutics Inc., down $2.47 to $2.54
Regulators put the company's experimental hepatitis C drug on hold after two patients were diagnosed with jaundice.
Carnival Corp., up 9 cents to $43.73
The cruise line company reported a larger profit and sales than analysts had expected.
Dow Chemical Co., down $1.01 to $48.50
The company will cut about 2,500 jobs and close some plants as it prepares to combine with DuPont.
Hess Corp., up $2.51 to $55.14
Energy companies traded higher with the price of oil on Tuesday.
Consolidated Edison Inc., down 53 cents to $79.20
Utility companies fell after making big gains over the last few days.