The newest model in the PharmaSafe® range of high containment valves has successfully achieved nanogram level performance. The PharmaSafe 'pro' is the latest iteration in the range of patented split valves, specifically developed to meet the demands for operator protection against increasingly potent ingredients. The PharmaSafe pro can achieve up to 0.1µg/m³ for the task duration. The valve achieves this high level of performance by utilizing a simple extraction process, which is integral to the valve, to minimise the volume of airborne contamination when the valve is separated, post transfer. The extraction system requirement is designed so that customers can commonly utilise existing onsite supply. The patented split valve containment technology has become the pharmaceutical and fine chemical industry standard for the contained transfer of toxic ingredients, by providing a common interface at each process stage.