Purdue Pharma said in a statement that the FDA accepted its application for Targiniq ER, an extended release tablet that combines oxycodone — the active ingredient in OxyContin — with the drug naloxone. The naloxone, which can reverse the effects of opioids, is intended to help make the medicine less likely to be abused.
A measure of the U.S. economy's health increased in October, suggesting consumers and businesses mostly shrugged off the 16-day partial government shutdown.The Conference Board says its index of leading indicators rose 0.2 percent in October to a reading of 97.5.
Businesses spent less last month on machinery, computers and most other items, lowering orders for U.S. long-lasting factory goods. The decline suggests companies may have been reluctant to invest during the 16-day partial government shutdown.
The number of Americans seeking unemployment benefits dropped 10,000 last week to a seasonally adjusted 316,000, a sign that workers are in less danger of being laid off. The Labor Department says the less volatile four-week average fell 7,500 to 331,750. Both the weekly jobless claims and the average have returned to pre-recession levels.
Beijing is waging a war against air pollution, one barbecue at a time. Authorities in the capital have destroyed more than 500 open-air barbecues "to cut PM2.5" — the tiny particulate matter in the air that can enter deep into the lungs.
U.S. consumers' confidence in the economy fell in November to the lowest level in seven months, dragged down by greater concerns about hiring and pay in the coming months.The Conference Board said Tuesday that its index of consumer confidence dropped to 70.4 from 72.4 in October.
The European Commission said in a statement Thursday that the companies — both of which are based in the U.S. — have agreed to dispose parts of their businesses producing and supplying cell cultures, "gene silencing" products and polymer-based magnetic beads.
In a warning letter posted online Monday, FDA regulators say that the Silicon Valley company has not shown that its tests are safe or effective despite "more than 14 face-to-face and teleconference meetings" and "hundreds of email exchanges."
Canada and Norway had challenged the ban on the grounds that it was inconsistent. It grants exceptions to support indigenous Arctic communities that export limited amounts of seal products and to protect fisheries' nets and their catch.
Qualcomm is being investigated by Chinese regulators for possible violations of the country's anti-monopoly law. The company said Monday that details of the investigation by the National Development and Reform Commission are confidential.
The director-general of the World Trade Organization says negotiators have failed to craft the first global trade deal in more than a decade, which could have given the world economy a $1 trillion boost. Roberto Azevedo says diplomats from the WTO's 159 members tried hard but "cannot cross the finish line here in Geneva" ahead of a summit where ministers were to have signed the deal in Bali, Indonesia, next week.
Merrell Williams Jr., a one-time Kentucky paralegal who took on Big Tobacco as a whistleblower who leaked internal documents exposing health risks and the addictiveness of cigarettes, has died in Mississippi, decades after he joined the fight that forever changed perceptions of smoking.
The Food and Drug Administration is lifting severe safety restrictions on the former blockbuster diabetes pill Avandia, citing recent data suggesting that the much-debated medication does not increase the risk of heart attack.The repeal means patients will no longer have to enroll in a special registry to be eligible to receive the drug.
That means methane may be a bigger global warming issue than thought, scientists say. Methane is 21 times more potent at trapping heat than carbon dioxide, the most abundant global warming gas, although it doesn't stay in the air as long.
A report released Friday by Sen. Robert Menendez of New Jersey, chairman of Senate Committee on Foreign Relations, said Bangladeshi authorities need to make further improvements in factory safety and labor rights. The report, compiled by staff of the committee's Democratic majority, acknowledged some progress, but said the presence of labor unions is still nominal.
A federal appeals court has tossed out a more than $6 million award to the family of a North Carolina teenager who died after being shocked with a Taser.In a 2-1 ruling Friday, the 4th U.S. Circuit Court of Appeals in Richmond upheld a jury's finding that Taser International was negligent in the 2008 death of 17-year-old Darryl Wayne Turner.
It is unclear whether the company or its executives will face criminal charges. Several lawyers who represent victims in lawsuits say health care companies charged with selling contaminated drugs often reach settlements with the federal government and agree to pay large fines.
For decades, presidential candidates' chances in Iowa were wounded if not doomed unless they backed federal support for ethanol, a boon to the state's corn-growing economy. That rule of politics collapsed resoundingly in the 2012 campaign when five of the six top Republican candidates said it was time for such intervention in the private market to end.
The Obama administration said Friday it will lose $139 million on a loan to struggling electric car maker Fisker Automotive Inc. after selling part of the loan to a private investor that immediately took the company into bankruptcy. Hybrid Technology LLC, the California car marker's new owner, said it plans to keep Fisker operating after it emerges from bankruptcy.
Chief executive Elon Musk said the fires, which occurred when metal road debris pierced the underbody of the cars at highway speeds, are extreme cases. He doesn't expect a recall and said his engineers are not working on any fixes for the battery-powered cars.
China's first unmanned stealth drone made its first test flight in the latest advance for the domestic arms industry, state media reported Friday.Photos and video of the tailless delta-wing drone flying were posted on the websites of People's Daily and other major outlets.
State officials say a locomotive manufacturer is establishing an assembly and fabrication plant in Knoxville, adding 203 jobs over the next three years.Officials say Knoxville Locomotive Works will establish the plant in Knoxville to satisfy new Environmental Protection Agency emission requirements for trains.
Tim Berners-Lee, who launched the Web in 1990, made the remarks as he released his World Wide Web Foundation's annual report tracking the Web's impact and global censorship. The index ranked Sweden first in Web access, openness and freedom, followed by Norway, the U.K. and the United States.
The Ohio Inspector General found that $34 million in requested refunds dating back several years were placed on pending status and therefore not paid out, according to the report, which said the practice violates Ohio tax law and dates to at least 1999. That doesn't include interest required to be paid on refunds.
Unemployment fell in 28 U.S. states last month, and employers added jobs in 34 states. The gains suggest recent improvements in the job market have occurred in most regions of the country. The Labor Department said Friday that unemployment rates rose in 11 states and were flat in 11. Employers cut jobs in 15 states.